A solvent action parametrization scheme has been developed combining relevant parameters of the solvent action on modern artists' paints to characterize the solvation and dissolving properties of different binding media. The new system combines different concepts used in solvent chemistry. It is based on the normalized and solute-dependent dimension [hδH + eET(30)cv]N. It comprises a polarity value ET(30)cv as the magnitude of the enthalpy, and a combined value representing the cavitation energy δH as an entropy-influencing factor. Forty-eight solvents were divided into five subgroups based on their interaction and structural properties. This binary scheme permits to reliably quantify spaces of efficiency. The graphical selectivity of the scheme was applied to four binding media systems (oil, alkyd, acrylic-, and acrylic-polystyrene) by determination of the swelling capacity of 48 solvents. The graphical visualization of the systematic parametrization of solvents permits one to judge the intermolecular interaction and other effects of solvation relevant to the restoration of painted artwork.